Presentation:
The patient presented with a mediastinal mass and marked weight loss. She experienced intermittent fever and episodes of breathlessness.
She was first seen three months ago but initially declined chemotherapy. She now returns with further clinical deterioration and has consented to commence treatment.
A right-sided pleural effusion had been aspirated once, but no pathological report is available.
A biopsy of the mediastinal mass confirmed diffuse large B-cell lymphoma (DLBCL). Comprehensive genomic profiling (CGP) is underway to determine whether it is of the germinal center B-cell (GCB) subtype or another variant.
Planning CHEMO., R-EPOCH
Targeted Therapy Note:
TARGT IndieGene Liquid - It is a pan solid cancer panel which profiles DNA/RNA alterations in 1212 genes along with Immunotherapy Biomarkers (TMB, MSI)